アスピリン内服中の大腿骨頚部/転子部骨折患者に対する早期手術についての検討

Early Surgery for Femoral Neck/Trochanteric Fractures in Patients on Aspirin Therapy

　高齢者ではアスピリン(バイエル薬品株式会社製バイアスピリン^®錠，エーザイ株式会社製バファリン^®81mg錠のいずれか)を内服中の患者が多く，今後さらに増加が予想されるが，アスピリンの術前休薬の必要性については明確ではない．アスピリン内服中(内服群)の大腿骨頚部/転子部骨折患者に対して，入院後6日間以内に手術を施行し，内服していない患者(非内服群)と比較することで，その安全性について検討した．内服群，非内服群間で出血性合併症に差は認めず，アスピリン内服例でも入院後6日以内で手術が可能であると思われた．

　The use of aspirin in the elderly will further increase in the future.　However, it is unclear whether aspirin should be stopped before surgical operations, and if it should, how many days prior to surgery it should be stopped.　We investigated the risk of hemorrhagic complications in patients being treated with aspirin who underwent surgery for femoral neck/trochanteric fractures.　We performed the surgical operations on the patients in this study within six days after their admission to the hospital and compared the outcomes of aspirin-treated patients (treated group) and non-aspirin-treated patients (non-treated group).　No differences in outcome were observed between the two groups, suggesting that surgery for femoral neck/trochanteric fractures can be performed within six days after admission of patients being treated with aspirin, without inducing severe hemorrhagic complications.