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Rhabdomyosarcoma Exhibiting Alveolar Features in the Absence of a Specific Gene Translocation. Case Report Guidong Li 1 , Akira Ogose 1 , Tetsuo Hotta 1 , Hiroyuki Kawashima 1 , Naoto Endo 1 , Hajime Umezu 2 , Chihaya Imai 3 , Masayuki Kubota 4 , Naoki Okuyama 4 , Yutaka Hirayama 4 , Atsushi Ogawa 5 , Keiko Asami 5 , Haruko Iwabuchi 5 1Division of Orthopedic Surgery, Graduate School of Medical and Dental Sciences, Niigata University 2Department of Pathology, Medical and Dental Hospital of Niigata University 3Division of Pediatrics, Graduate School of Medical and Dental Sciences, Niigata University 4Department of Pediatric Surgery, Graduate School of Medical and Dental Sciences, Niigata University 5Department of Pediatrics, Niigata Cancer Center Hospital Keyword: 横紋筋肉腫 , rhabdomyosarcoma , 胞巣型 , alveolar type , 染色体転座 , chromosome translocation pp.833-837
Published Date 2008/8/25
DOI https://doi.org/10.11477/mf.1408101350
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 We report a case of rhabdomyosarcoma that exhibited atypical alveolar featurs in the absence of a specific chromosomal translocation. The patient was a 14-month-old girl with a soft tissue mass on the lateral aspect of her right thigh. The diagnosis based on the fine-needle aspiration cytology findings was rhabdomyosarcoma, and wide resection was performed. The postoperative histopathologic examination revealed embryonal portions alternating with an alveolar pattern. The tumor differed from the typical alveolar type because of the paucity of fibrous septa and the presence of a large number of rhabdomyoblasts. Neither the t (2;13) or t (1;13) alveolar-type-specific translocation was identified. During the six years nine months since surgery multiple-metastases have occurred, and the primary tumor has repeatedly recurred.


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電子版ISSN 1882-1286 印刷版ISSN 0557-0433 医学書院

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