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Diagnosis of Vertebral Fractures due to Metastatic Spinal Tumor Using Bone Absorption Marker (u-NTx) Takahiro Iizuka 1 , Kazuo Noda 1 1Department of Orthopaedic Surgery, Kawasaki Hospital Keyword: u-NTx , 尿中NTx , spinal metastatic tumor , 転移性脊椎腫瘍 , vertebral compression fracture , 椎体圧迫骨折 , bone absorption marker , 骨吸収マーカー pp.681-685
Published Date 2005/6/1
DOI https://doi.org/10.11477/mf.1408100124
  • Abstract
  • Look Inside

 Diagnosing pathological spinal fractures may require further examination, e.g., by MRI and bone scintigraphy. Bone absorption was evaluated by U-NTx in 45 patients (average age 70.4 yo)with fresh vertebral fractures. U-NTx was significantly higher in those with pathological vertebral fractures than in those with osteoporotic fractures (tumor:109.2, osteoporosis:70.2, p=0.0337). U-NTx correlated slightly with the total number of metastatic lesions (p=0.0586). U-NTx presents bone absorption, however, so U-NTx is also influenced by metabolic bone changes, e.g., steroid intake, ovariectomy, gastrectomy, etc. U-NTx is useful and noninvasive, and we found it helpful in evaluating pathological changes in bone.


Copyright © 2005, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1286 印刷版ISSN 0557-0433 医学書院

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