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Some Observations on the clinical Application of Psychogalvanic Skin Pesponse (GSR) M. Katsumi 1 , M. Oka 1 , T. Murao 1 , K. Manabe 1 1Ist Department of Surgery, Osaka Univ. Medical School pp.238-241
Published Date 1957/4/1
DOI https://doi.org/10.11477/mf.1406200563
  • Abstract
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M.Katsumi, one of the authors,already reported that the most important center go-verning GSR is the hypothalamus and not the thalamus on his experiments.

From these facts we observed the changes of GSR on cases of epilepsy and examined the effects of neuroplegic phenothiazine deri-vatives on GSR.

During the petit mal seizure, GSR was absent, while 3 per second spike and wave EEG pattern and "eye-lid-reflection" were seen at the time.

But at the postconvulsive period of non-res-ponsiveness induced by cardiazol, GSR was witnessed, though it was smaller than before.Accordingly we can assume that petit mal seizure may influence upon the hypothalamus intensively.

Among the phenothiazine derivatives, Chlor-promazine, which has the strongest sympa-thicomimetic action, could depress GSR in the strongest degree, and Promethazine ranked next, but Diethazine, which has the strongest parasympathicomimetic action, rather acce-lerated GSR a little.

So GSR measurement may be available to indicate the sympathicomimetic effects of such neuroplegics.


Copyright © 1957, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 2185-405X 印刷版ISSN 0006-8969 医学書院

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