A Preliminary Study on the Early Detection of Pervasive Developmental Disorders at 18-month Check-up Yoko KAMIO 1 , Naoko INADA 1 1Graduate School of Human-Environmental Studies, Kyushu University, Fukuoka, Japan Keyword: Autism , Pervasive developmental disorder , Early detection , 18-month check-up , M-CHAT pp.981-990
Published Date 2006/9/15
DOI https://doi.org/10.11477/mf.1405100312
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 Objective:We aimed to determine whether the Japanese version of the Modified Checklist for Autism in Toddlers (M-CHAT) could identify Japanese children with PDD (Pervasive Developmental Disorders) at 18 months of age. Methods:A prospective cohort study was conducted on 659 children. The follow-up methods included two-stage screening and developmental evaluations with screen-positive children and their parents. Results:M-CHAT identified, as PDD, eleven children with PDD and four children without PDD but with developmental problems at 18 months of age. Children with PDD were significantly differentiated from typically developing children by the total number of failed items among the M-CHAT 23 items and failure on an item relating to social interest, imitation, joint attention, pretend play, and language. Conclusion:This preliminary study demonstrated that a 2-stage screening system using the Japanese version of M-CHAT can offer useful early detection of PDD at the age of 18 months.

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