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Remarkable Effect of Colforsin Daropate Hydrochloride in a Case of Low Output Syndrome following Coronary Artery Bypass Grafting Wakako Tamo 1 , Takeo Shibata 1 , Seiji Takahashi 1 , Masayuki Koyama 1 , Yuichi Ono 1 , Koh Takeuchi 1 , Kohzoh Fukui 1 , Shunichi Takaya 1 , Ikuo Fukuda 1 1Department of First Surgery, Hirosaki University School of Medicine Keyword: 塩酸コルホルシンダロパート , 冠状動脈バイパス術 , 低心拍出量症候群 , colforsin daropate hydrochloride , coronary artery bypass grafting , low output syndrome pp.953-957
Published Date 2002/9/15
DOI https://doi.org/10.11477/mf.1404902538
  • Abstract
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A 70-year-old woman treated for angina pectoriswas admitted to a hospital because of severe chestoppression.Immediate cardiac catheterization revealedsevere stenosis of the left main coronary trunk withthree vessel disease.She was referred to our hospitalwhere coronary bypass grafting was performed.Afterthe operation,she developed low cardiac output syn-drome.Although she was treated with cathecholamines,phosphodiesterase (PDE) III inhibitor,diuretic and so onwith intra aortic balloon pumping,her conditioncontinued to deteriorate.We started administration ofcolforsin daropate hydrochloride (CDH).After CDH thecardiac output and the urine volume increased, and thevascular resistance declined without hypotension whichoften occurs in administration of PDE III inhibitors.Inthe examinations after the operation,her ECG revealedno ischemic changes and coronary angiography revealedthat each graft was completely patent.CDH hasremarkable effects in acute cardiac failure with uniquemechanism and CDH can also have effects in low outputsyndrome following coronary artery bypass grafting.


Copyright © 2002, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1200 印刷版ISSN 0452-3458 医学書院

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