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A Case which Look upon Malignant Lymphoma with Massive Cardiac Involvement Munefumi Hotta 1 , Junzou Nagashima 1 , Toshika Nakamura 1 , Hirohiko Nobuoka 1 , Hideko Takeuchi 2 , Toshifumi Takakuma 2 , Fumihiko Miake 1 , Masahiro Murayama 1 12nd Department of Internal Medicine, St. Marianna University, School of Medicine 22nd Department of Pathology, St. Marianna University, School of Medicine Keyword: 悪性リンパ腫 , 心臓原発悪性リンパ腫 , 心嚢液貯留 , malignant lymphoma , malignant lymphoma primary involving the heart , pericardial effusion pp.713-716
Published Date 1995/7/15
DOI https://doi.org/10.11477/mf.1404901088
  • Abstract
  • Look Inside

Though malignant lymphoma is not a rare disease, cardiac malignant lymphoma is rare. The authors report the case of a 85-year-old female with primary malignant lymphoma involving the heart. The patient noticed dyspnea which gradually worsened until about 2 weeks before admission. At the time of admission the patient showed dominant orthopnea. The chest X-ray film revealed marked cardiomegaly associated with pleural effusion of both lung fields. Echocardiogram revealed pericardial effusion and roundshaped mass effect at the epicardium. On computed tomographic study of the chest, the location of the mass effect was identified at the superior anterior mediastinum. Mass effect was not identified on computed tomographic study of the abdomen. Cytological diagnosis of pericar-dial and pleural effusion revealed the presence of malig-nant lymphoma cell (class V). From these findings, pericarditis due to malignant lymphoma was diagnosed. The patient was treated with steroid and alkaloid. 1 week after the drugs administration had been started, her general condition seemed to improve. But after her blood pressure decreased suddenly she died of cardiac tamponade supposedly due to gross hemorrhage into the pericardium. Though autopsy could not be obtained, malignant lymphoma of cardiac origin was strongly suspected. From the literature, this type of malignant lymphoma is extremely rare and so deserved to be reported.


Copyright © 1995, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1200 印刷版ISSN 0452-3458 医学書院

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