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第一度房室ブロックは臨床上,虚血性心疾患,心筋炎,先天性心疾患を有する場合や,抗不整脈剤使用時,心臓外科手術後などにしばしばみられることがある。それにひきかえ2度房室ブロックは1度房室ブロックより頻度が少なく,多くは器質的心疾患を伴う例や,ジギタリス中毒の際に見られることが多い1)。こうした房室ブロックは正常人でもみられるが,一般の人に比較して,若い運動選手や活発な中年の人によくみられる2〜6)。
それ故房室ブロックの存在だけからは病的とは言えず病的かどうかの判定には,非観血的な方法として,休位変換7〜8)や運動および薬物負荷試験3,9,10),が利用されている。最近では観血的な方法として,ヒス束心電図(以下HBE)検査を行って,房室伝導障害の部位診断もなされるようになった11)。
Second degree A-V block is usually observed in patients with organic heart diseases. However it is also often found in normal subjects especially in young athletics or physically active middle aged persons. Responses to A-V conduction due to changing posture, exercise and administration of atropine sulfate were used to evaluate the atrioventricular disturbed function in order to clarify whether it is due to organic disturbance or functional one. Function of A-V conduction is evaluated by means of Master's step test and ambulatory ECG. Thirteen males and 6 females, 12 to 75 years old patients with second degree AV block on the routine ECG were studied. Second AV block consisted of 17 cases of Mobitz type I and 2 cases of Mobitz type II. In 12 cases out of 19 cases 24 hours electrocardiographic recordings were performed. The following results were obtained.
1. In 16 cases (84.2%) out of 19 cases second degree AV block disappeared and in 2 case (10.5%) second degree AV block was unchanged just after Master's two step test. In one case (5.3%) out of 19 cases Mobitz type I block advanced to Mobitz type II block. On a 15 years old school boy whose second AV block was unchanged by Master's double two step test exercise test by Ergometer was performed, by which the second degree AV block was disappeared.
2. In the cases whose second degree A-V block disappeared by exercise test, the block was observed mainly at night when their heart rate decreased less than day time by ambulatory ECG. From these findings it is suggested that A-V conduction disturbance may occur without any organic changes. On the other hand in a case whose Mobitz type I block was advanced to Mobitz type II, second degree AV block was oberved more frequently at day time during work than at night by ambularory ECG.
3. In 2 out of 19 cases in which second degree AV block was neither recovered nor advanced to Mobitz type II block organic AV conduction disturbance was found. Master's step test is a very simple and usefull method in order to evaluate atrioventricular function whether it is organic or not.
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