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Japanese

A Case Report of Bronchial Asthma with COPD, Improved Diurnal Changes in PEF with Budesonide/Formoterol Ken Iesato 1 , Naoko Kawada 1 , Kouichiro Tatsumi 1 1Department of Respirology, Graduate school of medicine, Chiba University Keyword: COPD合併喘息 , ピークフロー , BUD/FM配合剤 , bronchial asthma with COPD , peak flow , Budesonide/Formoterol pp.285-288
Published Date 2013/3/15
DOI https://doi.org/10.11477/mf.1404102179
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 Although the pathogenesis and the treatment differ between bronchial asthma and COPD, account for a high percentage among chronic respiratory diseases and an increasing in recent years. This case is a 75-year-old woman with a smoking history of 53 years, began to become aware of shortness of breath by movement 2 years ago. She visited our facility to receive detailed examination and was found to have obstructive ventilatory disorder and pulmonary emphysema. With her smoking history, we diagnosed COPD and began to start tiotropium. Her symptom alleviated but did not disappear completely. Wheeze and stridor were heard in the morning, she was diagnosed as having bronchial asthma with COPD. After the additional BUD/FM therapy, the circadian variation in peak flow improved and subjective symptoms(sputum, cough, etc.)alleviated. She thus followed a favorable course despite the complaint of shortness of breath during effort. Selected drugs differs between COPD and asthma, because of differences of the inflammatory cells and pathophysiological features, however, BUD/FM treatment is expected to exert anti-inflammatory effects, deserves to be considered when dealing with bronchial asthma with COPD.


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電子版ISSN 1882-1200 印刷版ISSN 0452-3458 医学書院

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