Japanese

Endoscopic Diagnosis of Gastric Epithelial Neoplasia Arising from the Fundic Gland Mucosa Hiroya Ueyama 1 , Takashi Yao 2 , Tomoyo Iwano 1 , Ryota Uchida 1 , Hisanori Utsunomiya 1 , Daiki Abe 1 , Shotaro Oki 1 , Nobuyuki Suzuki 1 , Atsushi Ikeda 1 , Noboru Yatagai 1 , Yoichi Akazawa 1 , Tsutomu Takeda 1 , Kohei Matsumoto 1 , Kumiko Ueda 1 , Mariko Hojo 1 , Akihito Nagahara 1 1Department of Gastroenterology, Juntendo University, School of Medicine, Tokyo 2Department of Human Pathology, Juntendo University, School of Medicine, Tokyo Keyword: 胃底腺型胃癌 , 胃底腺型腺癌 , 胃底腺粘膜型腺癌 , 胃型分化型腺癌 , 胃型腺腫 pp.1310-1322
Published Date 2021/9/25
DOI https://doi.org/10.11477/mf.1403202557
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 We analyzed the clinicopathological and endoscopic features of gastric epithelial neoplasia arising from the fundic gland mucosa in patients uninfected by Helicobacter pylori. Gastric epithelial neoplasia arising from the fundic gland mucosa was histopathologically classified into GAFG(gastric adenocarcinoma of fundic gland type), GAFGM(gastric adenocarcinoma of fundic gland mucosa type), GAGP(gastric adenocarcinoma of gastric phenotype), and PGA(pyloric gland adenoma). According to the cell differentiation findings, GAFG indicates differentiation toward fundic gland cells, GAFGM indicates differentiation toward foveolar cells and fundic gland cells, and GAGP and PGA indicate differentiation toward foveolar cells, pyloric gland cells and fundic gland cells. These neoplasms demonstrated a lower degree of atypia and malignancy than the common type of gastric cancer, and endoscopic resection was selected for treatment. The recognition of every endoscopic feature and the identification of tumor exposure on the surface and the relationship between surface mucosa and the underlying tumor are necessary for accurate endoscopic diagnosis of gastric epithelial neoplasia arising from the fundic gland mucosa in patients without H. pylori infection.


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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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