Pathology of Nonneoplastic Gastric Polyps Shinichi Ban 1 , Yoko Sato 1 , Jun Matsushima 1 , Taiki Sato 1 , Akiko Fujii 1 , Yuko Ono 1 , Ikuhiro Kobori 2 , Yasumi Katayama 2 1Department of Pathology, Dokkyo Medical University Saitama Medical Center, Koshigaya, Japan 2Department of Gastroenterology, Dokkyo Medical University Saitama Medical Center, Koshigaya, Japan Keyword: , 非腫瘍性ポリープ , 病理組織学的所見 , 背景粘膜 pp.829-839
Published Date 2021/5/25
DOI https://doi.org/10.11477/mf.1403202470
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 Sporadic/solitary nonneoplastic polypoid lesions arising in the stomach, including some benign lesions that were formerly considered nonneoplastic but have recently been referred to as neoplastic based on any genetic alterations, comprise the following two categories:lesions of the mucosa origin predominantly caused by epithelial change and lesions caused by a submucosal tumorous mass elevating the mucosa. The former includes fundic gland polyp and hyperplastic polyp, polypoid lesions that are most frequently found in the stomach. Rare Peutz-Jeghers type polyps could be lesions that need to be differentiated from hyperplastic polyps. Major lesions included in the latter type are hamartomatous inverted polyp, heterotopic pancreas, and inflammatory fibroid polyp ; in each of these, the relationship between the submucosal mass and the overlying mucosa is different. The recognition of the histopathologic architecture of each lesion including the findings of the background mucosa is an essential basis for the differential diagnosis of these lesions.

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