雑誌文献を検索します。書籍を検索する際には「書籍検索」を選択してください。

Stomach and Intestine(Tokyo) Volume 50, Issue 7 （June 2015）

胃と腸 50巻7号（2015年6月発行）

Japanese English

今月の主題診断困難な炎症性腸疾患

主題

indeterminate colitis（広義）の経過 Clinical Course of Indeterminate Colitis 平井郁仁 ¹ , 矢野豊 ¹ , 高津典孝 ¹ , 別府孝浩 ¹ , 石原裕士 ¹ , 二宮風夫 ¹ , 小野陽一郎 ¹ , 古賀章浩 ¹ , 金城健 ¹ , 佐藤祐邦 ¹ , 大門裕貴 ¹ , 久部高司 ¹ , 松井敏幸 ¹ , 東大二郎 ² , 二見喜太郎 ² , 今村健太郎 ³ , 田邉寛 ³ , 池田圭祐 ³ , 岩下明德 ³ Fumihito Hirai ¹ , Yutaka Yano ¹ , Noritaka Takatsu ¹ , Takahiro Beppu ¹ , Hiroshi Ishihara ¹ , Kazeo Ninomiya ¹ , Yoichiro Ono ¹ , Akihiro Koga ¹ , Ken Kinjo ¹ , Yuho Sato ¹ , Yuki Okado ¹ , Takashi Hisabe ¹ , Toshiyuki Matsui ¹ , Daijiro Higashi ² , Kitaro Futami ² , Kentaro Imamura ³ , Hiroshi Tanabe ³ , Keisuke Ikeda ³ , Akinori Iwashita ³ ¹福岡大学筑紫病院消化器内科 ²福岡大学筑紫病院外科 ³福岡大学筑紫病院病理部 ¹Department of Gastroenterology, Fukuoka University Chikushi Hospital, Chikushino, Japan ²Department of Surgery, Fukuoka University Chikushi Hospital, Chikushino, Japan ³Department of Pathology, Fukuoka University Chikushi Hospital, Chikushino, Japan キーワード： indeterminate colitis , inflammatory bowel disease unclassified , Crohn病 , 潰瘍性大腸炎 , 鑑別困難例 Keyword: indeterminate colitis , inflammatory bowel disease unclassified , Crohn病 , 潰瘍性大腸炎 , 鑑別困難例 pp.885-895

発行日 2015年6月25日 Published Date 2015/6/25

DOI https://doi.org/10.11477/mf.1403200344

PDF(5888KB)

有料閲覧

Abstract 文献概要
1ページ目 Look Inside
参考文献 Reference
サイト内被引用 Cited by

要旨●indeterminate colitis（以下，IC）は，Crohn病と潰瘍性大腸炎の鑑別診断困難例とされてきたが，その概念や定義は時代とともに変遷しつつある．本稿では，まず欧米におけるICの文献的レビューから，ICとinflammatory bowel disease unclassifiedを区別して用いる現状について解説した．さらにICの頻度，経過中の診断確定率，臨床的パターンについて述べ，自施設での経験例を提示した．

　The concept of IC（indeterminate colitis）has changed over the years. Originally, pathologists proposed IC as a diagnosis for colectomy specimens. As per this convention, patients with uncertain diagnosis of CD（Crohn's disease）or UC（ulcerative colitis）but having severe colitis were diagnosed with IC. However, the same terminology was adopted for patients who could not be diagnosed with CD or UC accurately when various factors including clinical, endoscopic, radiographic, and histologic features were considered. In Western countries, the new term“IBDU（inflammatory bowel disease unclassified）”is now used for patients with clinically chronic colitis who clearly have IBD but lack the definitive features of CD or UC. The term“indeterminate colitis”tends to be used for the same condition in Japan, and the definition of IC remains controversial. In this manuscript, we reviewed the literatures regarding IC and IBDU and described the frequency, rates of definite diagnosis, and clinical pattern of IC. The cases with IC that we recently experienced were diagnosed with definite CD in their clinical course. IC is not a definitive entity but a temporary diagnosis, and patients with IC as the first diagnosis need to be carefully followed-up for making the final diagnosis.