The Characteristic Finding of Histological Mixed Type of Gastric Adenocarcinoma in Magnifying Endoscopy Kazuyoshi Yagi 1 , Akiko Saka 1 , Yujiro Nozawa 1 , Atsuo Nakamura 1 , Hajime Umezu 2 1Department of Gastroenterology, Niigata Prefectural Yoshida Hospital, Tsubame, Japan 2Department of Pathology, Niigata University Medical and Dental Hospital, Niigata, Japan Keyword: 拡大内視鏡 , 胃癌 , NBI , 組織混在型胃癌 , SM癌 pp.1609-1618
Published Date 2013/10/25
DOI https://doi.org/10.11477/mf.1403113970
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 We studied the magnifying endoscopic findings of a histological mixed type of gastric adenocarcinoma, knowing that tubular adenocarcinoma(tub), papillary adenocarcinoma(pap)and undifferentiated adenocarcinoma(por)are independent histological types and two or three mixed-type are regarded as histological mixed type. The typical magnifying endoscopic finding of pap is a sphere-shaped pattern with loop-like vascular vessels. However, it is difficult to distinguish this magnifying endoscopic finding from tub with a papillary structure, so, the mixed-type adenocarcinoma of tub and pap is difficult to diagnose by magnifying endoscopy. In the case of mixed type of tub and por, if the component of por exists beneath the surface layer of the epithelium, it is not difficult to recognize because the typical magnifying endoscopic finding can be seen. However, if por is transformed from tub in a deep layer of the mucosa, the component of por cannot be diagnosed by magnifying endoscopy. The histological mixed-type is complex in its histological structure, so its magnifying endoscopic diagnosis is thought to be difficult compared with the histological single type of gastric adenocarcinoma.

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