Current Status and Issues of Transnasal Endoscopic Screening for Gastric Cancer:From the Viewpoint of Population Mass Screening Masayuki Inui 1,2 , Yoshikatsu Inui 1,2 , Susumu Ohwada 1,2 , Yuko Kondou 1,2 , Moriya Yoshikawa 2,3 , Naondo Sohara 4 1Inui Clinic of Internal Medicine, Takasaki, Japan 2Takasaki Medical Association, Takasaki, Japan 3Yoshikawa Clinic, Takasaki, Japan 4Shirakawa Clinic, Maebashi, Japan Keyword: 経鼻内視鏡 , 胃がんリスク(ABC)検診 , 内視鏡ABC分類 , H. pylori抗体 , ペプシノゲン値 pp.927-937
Published Date 2012/5/25
DOI https://doi.org/10.11477/mf.1403113481
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 The serum ABC classification determined by measuring serum H. pylori IgG antibody and serum pepsinogen levels is a simple and scientifically reliable method for mass screening of gastric cancer, by which a lower risk group of those not infected with H. pylori, Group A, is excluded from further endoscopic examination, and higher risk groups(Groups B, C, and D)are subjected to further endoscopic examination. The quality of images obtained by transnasal endoscopy is fully acceptable, and the present investigation indicated that the detection rate for gastric cancer was found to be a close equivalent to that of transoral high vision endoscopy. Furthermore, the serum ABC classification must be confirmed with the endoscopic ABC diagnosis since the serum ABC classification has several cutoff points and then a gray zone. Harmonization of serum ABC and endoscopic classification enables us to more precisely estimate the risk of gastric cancer. Moreover, higher risk groups and group that took eradication therapy for H. pylori should receive follow-up by a specialist.

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