Malignant Lymphoma of the Stomach: Collected eighty-seven cases H. Watanabe 1 1The First Department of Pathology, Niigata University, School of Medicine pp.909-910
Published Date 1980/9/25
DOI https://doi.org/10.11477/mf.1403112771
  • Abstract

 Eighty-seven cases of primary malignant lymphoma of the stomach was sent to a subcomittee from many institutions for detection of their characteristics.

 Macroscopically, the malignant lymphoma is divided into mass-forming type, superficial spreading type, giant rugal type and others; each, occupies 54.0%, 20.2%, 4.4% and 21.4%. Others comprise mixed type, and small early carcinoma-like patterns; Ⅱa, Ⅱc+Ⅲ, Ⅲ+Ⅱc, Ⅲ and Ⅱa+Ⅱc.

 The macroscopic characteristics of gastric malignant lymphoma are summarized as follows: (1) there are areas with intramural tumor pattern, (2) outline of the lesion is not necessarily clear especially in the cases of superficial spreading type, (3) mass-forming type is expansive and have sharp, circular, elevated ulcer-margin, (4) the stomach is flexible and not deformed, irrespective of presence of malignant lymphoma of mass-forming type or giant rugal type, and (5) the tumor has multiple erosions and ulcers.

 Histologically, the tumors, by Rappaport classification, consist of forty-four cases of histiocytic type (51%), thirty cases of poorly differentiated lymphosarcoma (35%), eight cases of well differentiated lymphosarcoma (3%), three cases of mixed type (3%) and two cases of Hodgkin's disease (2%).

 Macroscopic differentiation of gastric malignant lymphoma from other diseases is as follows: massforming type of lymphoma v.s. expansive ulcerating carcinoma, oat-cell carcinoma, carcinod and benign ulcer, and superficial spreading type of lymphoma v.s. benign lymphoid hyperplasia, multiple ulcers, superficial spreading carcinoma, leukemic infiltration and tuberculosis, and giant rugal type of lymphoma v.s. carcinoma of linitis plastica type, benign lymphoid hyperplasia, giant rugal hypertrophy and Cronkhite-Canada syndrome.

 Microscopically, malignant lymphoma must be differentiated from benign lymphoid hyperplasia, poorly differentiated medullary adenocarcinoma, carcinoma with lymphoid stroma, oat-cell carcinoma and leukemic infiltration.

Copyright © 1980, Igaku-Shoin Ltd. All rights reserved.


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