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Multiple Ulcers of the Small Intestine with Behçet Disease Y. Miyoshi 1 , N. Tamura 1 , K. Sakumoto 1 , H. Tanaka 1 , M. Gomyoda 2 12nd Department of Internal Medicine, Faculty of Medicine, Tottori University 2Department of Clinical Pathology, Faculty of Medicine, Tottori University pp.1629-1633
Published Date 1975/12/25
DOI https://doi.org/10.11477/mf.1403112121
  • Abstract
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 The patient, a woman 52 years old, had a chief complaint of abdominal pain along with stomatitis. She had been treated at the Department of Dermatology under a diagnosis of incomplete type of Behçet disease. She was referred then to our Department because of abdominal symptoms. X-ray and endoscopy here revealed multiple ulcers in the ileum. Surgical exploration was then done because they were considered intractable and penetration was suspected in some of them.

 The resected intestine showed 20 ulcers of various sizes over a segment from the terminal ileum to a point 90 cm oral from it. Histologic diagnosis was non-specific ulcer, but the majority of the ulcers were deep enough to be classified to Ul-IV, characterized further by hypertrophy and fibrinoid degeneration of the vascular walls not only in the floor of ulcers but in the submucosal layer of non-ulcerous areas as well. It could firmly be assumed that vascular changes be responsible for the origin of these ulcers.

 Literature of Behçet disease shows that among its protean symptoms intestinal ulcers tend to penetrate in the great majority of cases, constituting one of the most serious complications of this disease along with neurological disorders. The present case seems to warrant this fact. As compared with other non-specific ulcers, intestinal ulcer in Behçet disease is considered relatively specific.


Copyright © 1975, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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