胃異型上皮の1例

A CASE OF ATYPICAL EPITHELIUM OF THE STOMACH

Ⅰ．まえがき

　X線，内視鏡，直視下細胞診および生検の発展に伴い，微小病変に対する診断は非常に向上してきたが，それと共に良性と悪性の境界病変ともいえる異型上皮がクローズアップされてきた．我々も最近異型上皮と思われる症例を経験したので報告する．

　With the development of diagnostic procedures in diseases of the stomach, the number of cases with atypical epithelial focus has recently increased. Some cases hard to be determined whether they are of malignant nature belong to the atypical epithelial foci of the stomach.

　Here is a report of such a case suspected of early gastric cancer by gastrofiberscopic examination.

　The patient, a 66 years old male, visited our clinic with epigastric pain of two months' duration. There were no significant changes in the stomach by barium meal examination. Gastrofiberscopically a small mucosal elevation, slightly discolored on the surface, was demonstrated on the posterior wall of the corpus, and naturally early gastric cancer (type Ⅱa) was suspected.

　The brushing cytology under direct vision indicated class Ⅳ. The specimens taken by gastroscopic biopsy showed atypical epithelium.

　The histologicaol study of surgically resected stomach indicated atypical epithelium because the border of mucosal elevation showed gradual transition to the normal tissues, although structural and cellular atypism was evident.