Early Diagnosis of Gallbladder Cancer Using Conventional Ultrasonography as a Screening Filter Kenjiro Yasuda 1 , Hidekazu Mukai 1 , Sohtaro Fujimoto 1 , Masatsugu Nakajima 1 1Department of Gastroenterology, Kyoto Second Red Cross Hospital pp.497-505
Published Date 1986/5/25
DOI https://doi.org/10.11477/mf.1403110295
  • Abstract
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 Through recent progress of ultrasonography for digestive diseases, we can get an exact diagnosis of the gallbladder lesions easily. In this paper, the usefulness of ultrasonography as a screening filter for the early diagnosis of gallbladder cancer is discussed.

 From April in 1983 to December in 1985, the hepato-pancreato-biliary organs of 8,900 persons, who came to our hospital for health examination, were examined by ultrasonography. As a results of the health examination, gallstone was detected in 367 persons (4.1%). Polypold lesion was detected in 718 persons (8.1), Sixty cases of gallbladder polypoid lesion under 30 mm in size were examined histologically in 686 cases of cholecystectomy in the past five years.Comparing the size of the polypoid lesion with respective histological findings, it was confirmed that histological findings have no relation to the size of the lesions. For example, in the six cases of gallbladder cancer, three lesions were smaller than 10 mm in diameter.

 Ultrasonograms of 55 cases of gallbladder polypoid lesions were compared with their respective histological findings, and the ultrasonograms were devided into five groups, Type I: foamy high echogram, Type II: globular high echogram, Type III: papillary high echogram. Type IV: papillary solid echogram, Type V: nodular solid echogram. The echograms of adenocarcinoma and adenomyomatosis were detected, showing the echogram type IV or type V, except for one case of adenoma showing type III. It was impossible to make a differential diagnosis of these three diseases from ultrasonographic findings. Ultrasonogram of early gallbladder cancer in five cases (six lesions) showed the echogram type IV in two cases and type V in three cases.

 Thus, conventional ultrasonography is the most useful method as a screening filter for the early diagnosis of gallbladder cancer.But there is a limitation to the usefulness of conventional ultrasonography in diagnosing the quality of the small polypoid lesions and in the differentiation between benign and malignant lesions of gallbladder polyps.

Copyright © 1986, Igaku-Shoin Ltd. All rights reserved.


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