Clinico-pathological Aspects of Benign Polypoid Lesions of the Colon and Rectum T. Muto 1 1Department of Surgery, School of Medicine, University of Tokyo pp.739-749
Published Date 1973/6/25
DOI https://doi.org/10.11477/mf.1403108533
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 Benign polypoid lesions of the large bowel were divided into four groups on the basis of histological differences, and their histological features and clinical implication were described in detail with special reference to malignant potential.

 Metaplastic polyps are very common small sessile lesions in the rectal and colonic mucosa and there is no evidence that they are in any way related to adenoma or carcinoma. Usually they do not require any special treatment.

 Polyposis in colitis occurs as a result of mucosal inflammation and is better called inflammatory polyposis than pseudopolyposis. There is no evidence that inflammatory polyposis is related to the development of cancer in ulcerative colitis.

 Both juvenile polyp and Peutz-Jeghers polyp are hamartomatous in origin and are not precancerous.

 Adenoma is a benign neoplastic lesion of the intestinal epithelium. Tubular adenoma villous adenoma and papillary adenoma are words which describe the differet growth patterns of adenoma. The cytological changes are much the same and they are fundamentally due to the same disease.

 Polyp can be single or multiple and numerous polyps make polyposis.

 Adenoma has malignant potential which is more closely related to the size of the tumour than the difference of the growth patterns. The idea by Morson that for purpose of clinical diagnosis and treatment, the best criterion for malignancy is invasion through the line of the muscularis mucosae was introduced. If there is no submucosal invasion, the polyp will behave as a benign lesion, provided that it is completely removed. The management of adenoma and so-called malignant-polyp was also described in detail.

Copyright © 1973, Igaku-Shoin Ltd. All rights reserved.


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