Two Cases of Carcinoma of Appendix with Different Mode in Metastasis T. Matsuo 1 , T. Yao 1 , K. Miyasaki 2 1Internal Medicine, Hyogo Prefectual Awaji Hospital 2Devision II, Department of Pathology, School of Medicine, Kobe University pp.1381-1385
Published Date 1973/10/25
DOI https://doi.org/10.11477/mf.1403108509
  • Abstract
  • Look Inside

 Primary carcinoma of appendix is uncommon disease and divided into three types according to the pathological appearance; carcinoid type, malignant mucocelle type that produces pseudomyxoma peritonei and colonic type.

 Two patients with pseudomucinous adenocarcinoma of appendical origin showing different mode in metastasis were reported. Case 1 is a typical case of malignant mucocelle which was complicated with pseudomyxoma peritonei, while case 2 is clinically a colonic type with massive liver metastasis but histologically is closer to case 1.

 Case 1. A 63-year-old man was admitted to our clinic, complaining of lower abdominal pain of one week's duration. During hospitalization he underwent frequent abdominal paracentesis because of rapid accumulation of ascites. He deteriorated into cahexia and died. Postmortem examination revealed pseudomyxoma peritonei originating from appendix. Histologically it was ascertaind as adenocarcinoma with remarkable mucin production corresponding to malignant mucocelle type.

 Case 2. A 68-year-old man was admitted to our clinic because of epigastric discomfort. Laboratory findings showed increased E. S. R., anemia and elevated serum alkaline phosphatase level. Postmortem examination showed cauliflower like tumor which probably originated from the mucosa of appendix and invaded into mucosa of cecum, and had large metastasis in the liver. Histologically adenocarcinoma containing much mucin was confirmed. Although histological appearance of case 2 was considered as malignant mucocelle type that resembled very much to that of case 1, it is interesting to note that the mode of metastasis was that of colonic type.

Copyright © 1973, Igaku-Shoin Ltd. All rights reserved.


電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院