Duodenal Adenoma Developing Cancer after Follow-up for 4 Years, Report of a Case Mamoru Suzuki 1 , Shigeru Suzuki 1 , Toshiaki Nakasako 1 , Toshihide Imaizumi 1 , Masae Banno 2 , Michio Fukushima 2 1Institute of Gastroenterology, Tokyo Woman's Medical College Keyword: 十二指腸腺癌 , 腺腫 , 腫瘍切除 pp.681-685
Published Date 1993/6/25
DOI https://doi.org/10.11477/mf.1403106192
  • Abstract
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 The patient was a 66-year-old man. Screening upper Gastrointestinal endoscopic examination disclosed a small elevated lesion, about 1.5 cm in size, in the second portion of the duodenum. Histological examination of the biopsy specimen revealed a duodenal adenoma with a epithelial hyperplastic change and columnar epithelial atypic. He underwent multiple endoscopic examinations with biopsy, twice or three times a year, in the 3 years and 10 months since initial examination. Every histological examination of the biopsy specimen showed adenoma except for the 10th examination which revealed adenocarcinoma. Surgical resection of the lesion was performed through duodenotomy. Histological study of the resected specimen showed well differentiated adenocarcinoma. The follow-up study of the duodenal adenoma was valuable in this case.

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