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要旨 EMR(endoscopic mucosal resection),縮小手術の対象になりうる20
mm以下の陥凹型分化型胃癌264病変を対象にsm2以深浸潤の診断能を検討した.sm2以深癌は,①大きさでは10mm以下では6%,11~15mmで29%,16~20mmでは21%存在した.②占拠部位でsm2以深への浸潤率に差がみられた.10mm以下では,胃体部後壁,前庭部後壁は,sm2以深浸潤例はなかった.③形態的所見ではsm2以深癌の70%が診断可能であった.④X線検査の圧迫法による透亮像,遠景観察の内視鏡像で陥凹辺縁の隆起の存在はsm2以深の病変の可能性が高かった.⑤sm以深癌の潰瘍合併率は10mm以下で12%,11~15mmで32%,16~20mmで22%であり,潰瘍合併の診断能は50%以下であった.sm2以深の診断には病変の占拠部位,大きさ,形態的所見,EUSの所見を総合的に判断する必要がある.
Two hundred sixty four lesions of the depressive type differentiated gastric cancer less than 20 mm in size, which would be an indication for EMR or limited surgery, were evaluated for the detectability of invasion deeper than the sm2. Characteristics of the gastric cancer with invasion deeper than the sm2 were summarized as follows: 1) the percentages of the sm2 cancer were 6% in the lesions less than 10 mm in size, 29% in those larger than 11 mm and smaller than 15 mm, and 21% in those larger than 16 mm and smaller than 20 mm. 2) there was a difference in the rates of invasion deeper than the sm2 among locations, namely, there was no lesions with invasion deeper than the sm2 in the posterior wall of the gastric body and the antrum. 3) seventy percent of the cancers with invasion deeper than the sm2 could be detected by the macroscopic findings. 4) a translucent area by the pressure method in the radiologic examination and a surrounding elevation around depressive lesion by a distant view of endoscopic examnation suggested a lesion with invasion deeper than the sm2. 5) concomitant rates of gastric ulcer and the sm2 cancer were 12% in the cancer lesions less than 10 mm in size, 32% in those larger than 11 mm and smaller than 15 mm, and 22% in those larger than 16 mm and smaller than 20 mm. Diagnostic ability in the case of a gastric cancer with ulcers was less than 50%. Diagnosis of the lesions with invasion deeper than the sm2 should be based on the location, size, morphological findings, and EUS findings of the lesions.
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