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要旨 近年,マルチスライスCTの普及と解析ソフトの精度向上により,大腸癌スクリーニングにCTC(CT colonography)が臨床応用され,精度の高い検査法として認識され始めている.また,CTCには検査の客観性や再現性があり,標準化しやすい点や苦痛の少ない低侵襲性な検査という点からスクリーニング法としての潜在能力も高い.当センターではCTCによる大腸癌スクリーニングを導入し,その精度は感度91.4%,特異度92.4%,陽性反応的中度69.6%,陰性反応的中度98.3%,正診率92.3%,癌発見率0.21%と良好であった.CTCは大腸癌スクリーニングとして,その役割を十分果たすことのできる“新しい大腸癌検査法”になり得ると考えられる.
In recent years, CTC(CT colonography)has been clinically applied in the screaning of colorectal cancers, and is regarded highly for its diagnostic accuracy. This has become possible because of widespread use of multi-slice CT and increased use of analysis software. In addition, CTC, which yields objective and reproducible results, is a high-potential screening method, in that it is a low-invasive test associated with only mild distress, and can be easily normalized. In this center, screening for colorectal cancers with CTC is being conducted, with its accuracy being proved by statisical data : sensitivity(91.4%), specificity(92.4%), PPV(69.6%), NPV(98.3%), proper diagnosis rate(92.3%), and rate of detecting cancer(0.21%). CTC is considered to have the potential to become a“new test for colorectal cancers”, and can play an important role in screening for such cancers.
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