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Endoscopic Diagnosis of Upper Gastrointestinal Infectious Diseases Nobuhiro Sakaki 1 1Department of Endoscopy, Tokyo Metropolitan Komagome Hospital Keyword: 上部消化管感染症 , 寄生虫 , HIV , Helicobacter pylori , 胃炎 pp.259-266
Published Date 2002/2/26
DOI https://doi.org/10.11477/mf.1403103446
  • Abstract
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 Infectious diseases of the upper-gastrointestinal (UGI) tract have been the object of deep interest since the 1980s when the human immunodeficiency virus (HIV) and Helicobacter pylori (H. pylori) were discovered. Almost all pathogens infecting the UGI tract were too small to observe by endoscopy alone. Histological diagnosis using biopsy specimens taken from the infected area is necessary to ensure a correct diagnosis. Only a few lesions, such as the esophageal Cytomegalovirus ulcer in AIDS patients, are easily diagnosed from their characteristic endoscopic findings. Therefore, when an endoscopic examination is performed for patients with an infectious disorder, biopsies should be taken even when the disorder is non-specific and even from endoscopically normal areas.

 On the other hand, H. pylori is changing the role of endoscopic examination for the UGI tract. Many localized lesions located in the UGI tract; such as, peptic ulcer, MALT lymphoma, hyperplastic polyp and carcinoma are present in H. pylori-gastritis mucosa. Furthermore, these lesions except for carcinoma often improve after successful H. pylori eradication therapy. New criteria are needed for assessing the effect of eradication therapy and for endoscopic follow-up after treatment.


Copyright © 2002, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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