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Differential Diagnosis Through Comparison of Endoscopic Findings Concerning Superficial Gastric Lymphoma and Chronic Gastritis Kin-ichi Yokota 1 , Hiroki Tanabe 1 , Jiro Watari 1 1The Third Department of Internal Medicine, Asahikawa Medical College Keyword: 胃悪性リンパ腫 , 胃MALTリンパ腫 , 内視鏡診断 , PCR , Southern blot pp.61-68
Published Date 2001/1/25
DOI https://doi.org/10.11477/mf.1403103131
  • Abstract
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 Endoscopic features of superficial gastric lymphomas are presented focusing on the differences from those of chronic gastritis. Superficial gastric lymphomas tended to be low-grade MALT lymphomas or to have low-grade component (83% : 19/23), to be limited to the submucosal layer (83% : 19/23), and to involve Helicobacter pylori infection (83% : 15/18) . According to endoscopic features, superficial gastric lymphomas were subdivided into six types. Except IIc-like type and submucosal tumor type, endoscopic findings of the remaining 4 types of lymphomas resemble those of chronic gastritis. Multiple-erosion type lymphomas give rise to small round erosions in the slightly thickened muddled mucosal area, and are different from flat erosive gastritis and atrophic gastritis. Cobblestone-mucosa type lymphomas give rise to coarse granules surrounded by ditch-like erosions. We found peculiar cases of chronic gastritis showing cobblestone mucosa indistinguishable from this type of lymphoma. Partial-fold-swelling type lymphomas give rise to fine reddish erosions with uneven surface found on partially-enlarged folds, and which are different from rugal hyperplastic gastritis. Varioliform type lymphoma resembles lymphocytic gastritis. Reactive lymphoid hyperplasia of the stomach, which has polyclonal immunoglobulin gene rearrangement and is histologically different from MALT lymphoma, shows ulcerative-lymphoma-like ulcer and on being cured by anti-ulcer therapy, it gives rise to flat mucosa.


Copyright © 2001, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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