Crohn's Disease and Ulcerative Colitis were Observed Synchronously, and Followed up for Six Years, Report of a Case Yuiko Ishimoto 1 , Hidenobu Watanabe 2 , Yoichi Ajioka 2 , Terasu Honma 1 , Kazuhito Sugimura 1 1The Third Department of Internal Medicine, Niigata University School of Medicine 2The First Department of Pathology, Niigata University School of Medicine Keyword: 潰瘍性大腸炎 , Crohn病 , 合併病変 , 非乾酪性類上皮細胞肉芽腫 , HLA pp.223-229
Published Date 2001/2/25
DOI https://doi.org/10.11477/mf.1403103116
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 A 17-year-old male was admitted to the hospital because of watery diarrhea and hematochezia. The first colonoscopy revealed diffusely edematous and fragile mucosa all over the colorectum and a diagnosis of ulcerative colitis was made. Retrospectively, it was noticed that the biopsy specimen from the ascending colon contained a non-caseating epithelioid cell granuloma. Four years later, the patient relapsed presenting proctosigmoiditis, with stricture of the ileo-cecal valve and skipped ileal deep ulcer. Histological findings of biopsy specimens taken from the rectum and sigmoid colon were compatible with ulcerative colitis, and those from the terminal ileum and ascending colon showed granulomas, which were compatible with Crohn's disease.

 So, we suggest this patient might have both Crohn's disease and ulcerative colitis concomitantly.

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