Changing Trends of Early Gastric Cancer in Japan Chika Kusano 1,2 , Tadakazu Shimoda 2 , Hirokazu Taniguchi 2 , Hitoshi Katai 3 , Ichiro Oda 1 , Takuji Gotoda 1 1Endoscopy Division, National Cancer Center Hospital, Tokyo 2Clinical Laboratory Division, National Cancer Center Hospital, Tokyo 3Gastric Surgery Division, Department of Surgical Oncology, National Cancer Center Hospital, Tokyo Keyword: 胃癌 , 早期胃癌 , 時代的変遷 , 内視鏡治療 , Helicobacter pylori pp.465-471
Published Date 2009/4/24
DOI https://doi.org/10.11477/mf.1403101619
  • Abstract
  • Look Inside
  • Reference
  • Cited by

 We examined the changing trend of early gastric cancer in Japanese, who underwent surgery and endoscopic resection from 1962 to 2005 in the National Cancer Center Hospital(Tokyo, Japan). Early stage gastric cancer(T1)has been increasing especially from 1990. The rate of early gastric cancer among all gastric cancers is 71.2% in 1980-90 and 82.1% in 2000-2005. According to this fact, the endoscopic resection rate of all early gastric cancers has shown a remarkable increase since 2000. The size of early gastric cancer is smaller than that seen previously and the ratio of intramucosal cancer is increasing. This phenomenon reflects the development of endoscopic technique and progression of pathological diagnosis with biopsy.

 In recent years, the life style of Japanese has changed to a Western style. Also, the incidence of Helicobacter pylori infection in the second generation is low, as is the incidence or distribution of intestinal metaplasia. From such a situation,qualitative alteration is expected, as the location and histological type of early gastric cancer will be changed.

Copyright © 2009, Igaku-Shoin Ltd. All rights reserved.


電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院