Pharyngeal and Esophageal Melanosis Accompanied by Superficial Esophageal Carcinoma, Report of a Case Hirofumi Kawakubo 1 , Tai Omori 1 , Hitoshi Sugiura 2 , Akira Yokoyama 3 1Department of Surgery, Kawasaki Municipal Hospital, Kawasaki, Japan 2Department of Pathology, Kawasaki Municipal Hospital, Kawasaki, Japan 3Department of Internal Medicine, National Hospital Organization Kurihama Alcoholism Center, Yokosuka, Japan Keyword: 食道melanosis , 食道癌 , 食道静脈瘤 , アルコール依存症 , 食道melanocytosis pp.364-368
Published Date 2008/3/25
DOI https://doi.org/10.11477/mf.1403101304
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 A 61-year-old male, diagnosed with esophageal superficial carcinoma, esophageal varices and melanosis of the pharynx and esophagus by upper digestive endoscopy was referred to our hospital. Esophageal carcinoma was treated by endoscopic mucosal resection(EMR)using the EEMR-tube method, and esophageal varices were treated by endscopic variceal ligation(EVL). Melanosis of the pharynx and esophagus are being followed up by endoscopy. Histological examination revealed pigmented melanocytes amongst the keratinocytes in the epithelium. Melanosis has been frequently observed in the upper aerodigestive tract of Japanese heavy-smoking alcoholic men, so this indicates that the presence of esophageal melanosis can lead to a high risk for neoplasms of the esophagus.

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