Clinicopathological Findings of Benign Esophageal Tumors and Tumor-like Conditions Yasuhiro Takaki 1 , Akinori Iwashita 2 , Keisuke Ikeda 2 , Seiji Haraoka 2 , Hiroshi Tanabe 2 , Kaname Oshige 2 , Atsuko Ota 2 , Nobuaki Nishimata 2 , Toshiyuki Matsuda 1 1Department of Gastroenterology, Fukuoka University, Chikushi Hospital, Chikushino, Japan 2Department of Pathology, Fukuoka University, Chikushi Hospital, Chikushino, Japan Keyword: 食道良性腫瘍 , 食道腫瘍 , 腫瘍様病変 pp.279-288
Published Date 2008/3/25
DOI https://doi.org/10.11477/mf.1403101289
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 For rare tumors that develop in the esophagus and other tumorous lesions, clinicopathological findings from our own cases, together with features and diagnostic key points given in the literature, were outlined. All are rare lesions and making a precise clinical diagnosis is difficult;but for key points in differential diagnosis, the following can be listed: (1) Both xanthomas, which are small yellowish nodules, and an esophageal sebaceous gland are lesions that develop within the mucosa and therefore can be diagnosed from a biopsy. Due to the difference in the sites of involvement within the mucosa, endoscopic observations are sufficient for differentiation. (2) Fibrovascular polyps, lipoma and inflammatory fibroid polyps are all large submucosal tumor-like polyps that resemble each other under macroscopic observation: Differential diagnosis is possible based on their morphological features. In addition, the sites of involvement within the esophagus may be a key point in differentiation. (3) For pseudomalignant erosion, which seemingly shows malignant cell-like atypia under pathological examination, and epidermization that requires differentiation from 0-IIa tumors of white coloration, it is diagnostically important to note these possibilities in both clinical and pathological examinations. (4) Squamous papilloma commonly presents a polypoid lesion but on rare occasions, flat-type papillomas with lateral extensions have been noted.

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