Schönlein-Henoch Purpura Kiyotaka Okawa 1 1Department of Gastroenterology, Osaka City General Hospital Keyword: Schönlein-Henoch紫斑病 , 消化管病変 , 十二指腸病変 , 大腸病変 , 紫斑様病変 pp.559-565
Published Date 2003/4/24
DOI https://doi.org/10.11477/mf.1403100915
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 Schönlein-Henoch purpura is a disease secondary to vasculitis of capillaries and arterioles. Its major signs are skin symptoms, abdominal symptoms, articular symptoms and kidney disorder. Patients with this disease often experience abdominal symptoms (abdominal pain, in particular). Endoscopically, this disease presents with diverse features, including redness, purpuric lesions, edema, erosion and ulcers. Regarding the mechanism for the onset of this disease, it is thought that vasculitis elevates vascular permeability, leading to effusion, bleeding, redness and purpuric lesions, and that if vascular lesions are severe, thrombi are formed, leading to ischemic changes which can cause edema, erosion and ulcers. Duodenal lesions associated with this disease often develop in the second through to the fourth portions of the duodenum and they frequently assume the form of multip le ulcerative lesions. Red spots, resembling purpura, are often seen on the stomach and large intestine of patients with this condition.

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