Secondary Linitis Plastica Type Transverse Colon Carcinoma Discovered 11 years After Total Gastrectomy for Gastric Carcinoma, Report of a Case Satoshi Okabe 1 , Touichirou Takizawa 2 , Morio Koike 2 1Department of Surgery, Tokyo Medical and Dental University 2Department of Pathology, Tokyo Medical and Dental University Keyword: 横行結腸癌 , 続発性linitis plastica型大腸癌 , 胃癌 pp.1855-1861
Published Date 2003/12/25
DOI https://doi.org/10.11477/mf.1403100715
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 We were noticed during a periodic colonoscopic examination that circumferential stenosis of the transverse colon had appeared in a 75-year-old male patient, who underwent total gastrectomy for advanced gastric carcinoma 11 years ago. Pathologic examination of the biopsy specimen revealed the invasion of poorly differentiated adenocarcinoma into the submucosa. Barium enema examination demonstrated ill-defined circumferential stenosis and fixed transverse parallel folds at the distal transverse colon. We performed a resection of the transverse colon and a part of the liver and abdominal wall involved by the cancer. Through pathological examination of the frozen section, we diagnosed small nodules on the intestinal mesentery as peritoneal dissemination of gastric carcinoma. On pathological investigation of the transverse colon, poorly differentiated adenocarcinoma invading from the mucosa through the serosal surface was observed. It showed the configuration of so-called linitis plastica type carcinoma. The mucous staining of the mucosal layer of the carcinoma in the transverse colon was the same as that found in gastric carcinoma. It was mainly composed of signet-ring cell carcinoma with PAS positive mucous.

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