Special Histopathologic Type of Esophageal Carcinoma (Non-Squamous Cell Carcinoma) : Point of View from the Radiological Findings Yutaka Imai 1 , Rena Nagashima 1 , Hiroyasu Makuuchi 2 , Hideo Shimada 2 , Yuko Kato 3 1Department of Radiology, Tokai University School of Medicine 2Department of Surgery, Tokai University School of Medicine 3Department of Diagnostic Pathology, Tokai University School of Medicine Keyword: 食道癌 , 特殊組織型 , X線診断 pp.301-309
Published Date 2005/3/25
DOI https://doi.org/10.11477/mf.1403100038
  • Abstract
  • Look Inside
  • Reference
  • Cited by

 Any special histopathologic type of esophageal carcinoma, that is non-squamous cell carcinoma is very rare. We have encountered 51 cases of non-squamous cell carcinomas, including 15 cases of basaloid carcinoma, 14 cases of undifferentiated small cell carcinoma, 8 cases of carcinosarcoma, 7 cases of adenosquamous carcinoma, 2 cases of adenoid cystic carcinoma, 2 cases of malignant melanoma and one case of mucoepidermoid carcinoma and two other tumors.

 Most of these tumors appeared as polypoid lesions and radiographic study should be carried out observing the shape and height of the tumors, their type of elevation, their surface configuration, and the intraepithelial tumor spread. Although some squamous cell carcinomas infiltrated mainly into the subepithelial layer, the protruding tumors covered with a smooth surface and a steep boarder of elevation were highly suggestive of non-squamous cell carcinoma, especially undifferentiated small cell carcinoma and adenoid cystic carcinoma. On the other hand, basaloid carcinomas were observed as ill-defined and having gradual elevation. Protruding lesions with nodular and irregular surface were produced by the proliferation of many cancer cell nests, and these lesions were suggestive of basaloid carcinoma and undifferentiated small cell carcinoma. Radiological findings of these tumors showed a smooth nodular surface and a gentle line of gutter between the nodules, differing from the findings in squamous cell carcinoma. While adenoid cystic carcinoma showed a broad-based tumor, malignant melanoma tended to be a semi-pedunculated lesion with a narrow base. The special histopathologic types of esophageal carcinoma in the advanced stage metastasize more easily than ordinary squamous cell carcinomas. So the early detection and diagnosis of these tumors plays an important role in determining prognosis.

Copyright © 2005, Igaku-Shoin Ltd. All rights reserved.


電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院