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要旨●患者は60歳代,女性.定期の大腸内視鏡検査で盲腸に25mm大の表面隆起+隆起型病変を認めた.病変の表面隆起部はJNET分類Type 1,表面構造は開II・伸II型pit patternを呈しており,SSLを基盤とする病変と考えられた.隆起部自体は5mm大で表面隆起部の辺縁に存在し,JNET分類Type 2B,表面構造はVI型pit patternを呈しており,この部分で癌化しているものと推測した.内視鏡診断はSSLD,隆起部は本邦の粘膜内癌相当と考えESDを施行した.病理診断は,adenocarcinoma(tub1)in SSL,pT1a(SM 850μm),Ly0,V0,BD1,pHM0,pVM0であった.経過観察の方針とし,現在3年間無再発の状態を維持している.
A female patient in her 60s underwent a routine screening colonoscopy, during which a 25mm lesion was found in the cecum. The lesion had a flat part and a nodular part.
The flat part showed NBI classification of JNET Type 1, and magnified chromoendoscopy revealed Type II-O(open-shape)and II-L(long)pit patterns. The small nodular part was located at the margin of the flat area, and this nodule showed JNET Type 2B NBI classification, with magnified chromoendoscopy revealing a Type VI pit pattern. These findings suggested a sessile serrated lesion(SSL)with a cancerous part, whose estimated invasion depth was to be confined to the mucosa(SSLD, cTis). Endoscopic submucosal dissection(ESD)was performed for complete lesion resection. The pathological diagnosis was a well-differentiated adenocarcinoma(tub1)in an SSL, staged as pT1a with submucosal invasion of 850μm, Ly0, V0, BD1, HM0, and VM0.

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