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A case of bilateral isolated choroidal melanocytosis Hiroko Katakura 1 , Nobuyuki Kurosawa 1 , Masaaki Sakamoto 1 , Shigeki Machida 1 1Department of Ophthalmology, Dokkyo Medical University Saitama Medical Center pp.1148-1156
Published Date 2025/9/15
DOI https://doi.org/10.11477/mf.037055790790091148
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Abstract Purpose:Isolated choroidal melanocytosis is a rare disease characterized by congenital melanocytic choroidal pigmentation without associated scleral or cutaneous pigmentation observed in ocular and cutaneous melanocytosis. This report presents a case of isolated bilateral choroidal melanocytosis.

Case:A 56-year-old woman was referred to our department for further evaluation of diabetic complications. At the initial examination, her corrected visual acuity was 1.2 in both eyes, intraocular pressure was 20 mmHg in both eyes, and no remarkable findings were observed in the anterior segment or ocular media. Ultra-wide-angle fundus photography revealed 360° annular hyperpigmentation in the fundus of both eyes. Fundus autofluorescence and fluorescein angiography results were normal;however, late indocyanine green angiography revealed hypofluorescence consistent with the lesion. Optical coherence tomography showed no structural changes in the retina or choroid but detected thinning of the ganglion cell complex due to glaucoma. The electroretinogram demonstrated a decreased amplitude of the photopic negative response, which reflects retinal ganglion cell function, while other components remained normal.

Conclusion:In this case, extensive choroidal pigmentation was observed without the scleral or cutaneous pigmentation observed in ocular and cutaneous melanocytosis. Since no structural or functional abnormalities were detected in the lesion, a diagnosis of bilateral isolated choroidal melanocytosis was made.


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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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