腺癌および大細胞内分泌癌への分化を伴う成人型肺芽腫の1例

Pulmonary Blastoma with the Differentiation of Adenocarcinoma and Large Cell Neuroendocrine Carcinoma in an Adult Patient；Report of a Case

はじめに　肺芽腫は非常にまれな肺悪性腫瘍であり，原発性肺癌のうち0.25～0.5％程度を占める．高分化胎児型腺癌，胸膜肺芽腫も亜型として含まれていたが，1999年の世界保健機関（WHO）分類により，二相性肺芽腫（BPB）のみが肺芽腫として分類されるようになった1）．われわれは，健診をきっかけに発見された腺癌および大細胞内分泌癌への分化を伴う成人型肺芽腫の1手術例を経験したので報告する．

A 63-year-old man was pointed out a mass lesion in his chest X-ray at a medical checkup and referred to our hospital for further examination. Chest computed tomography showed a 4 cm-diameter tumor in the left upper lobe. He was diagnosed with adenocarcinoma by bronchoscopic biopsy. Therefore, we performed left upper lobectomy. The tumor was diagnosed as pulmonary blastoma with the differentiation of adenocarcinoma and large cell neuroendocrine carcinoma.