僧帽弁置換術後に血栓弁を生じた抗リン脂質抗体症候群の1例

Bioprosthetic Mitral Valve Thrombosis in Patient with Antiphospholipid Antibody Syndrome；Report of a Case

はじめに　抗リン脂質抗体症候群（APS）は動脈や静脈の血栓塞栓症をきたし，特に心臓血管外科領域の周術期および外来経過観察中にも注意深い管理が必要となる疾患である．われわれは生体弁による僧帽弁置換術（MVR）施行後，早期に血栓弁を生じた患者に対し，再弁置換術を行った症例を経験したので報告する．

A 66-year-old woman with primary antiphospholipid antibody syndrome （APS） was admitted due to severe dyspnea. Eight months prior to admission, she underwent bioprosthetic mitral valve replacement for mitral valve stenosis and regurgitation. Transthoracic echocardiogram showed thickening bioprosthetic valve leaflets and severe valve stenosis. Emergency reoperation for artificial valve failure was performed. The explanted bioprosthetic valve showed massive thrombus formation. After the operation, she started strict anticoagulant and antiplatelet therapies and was discharged without recurrence of valve thrombosis.