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Outcome of Limited Resection for Early Stage Non-small Cell Lung Cancer Tomohiro Murakawa 1 , Yohei Taniguchi 1 , Tomohito Saito 1 , Hiroshi Matsui 1 , Haruaki Hino 1 1Department of Thoracic Surgery, Kansai Medical University Keyword: non-small cell lung cancer , limited resection , segmentectomy , wedge resection pp.32-37
Published Date 2019/1/1
DOI https://doi.org/10.15106/j_kyobu72_32
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Objectives:Recent advancement in detection of small-sized early-stage lung cancer has made limited lung resection with curative intent a practical and vital option. In this retrospective study, we investigated the validity of choice of procedures at our institute with examining the survival outcomes of lung cancer patients who underwent surgery.

Methods:Data from consecutive patients with cTanyN0M0 lung cancer who underwent surgery between January 2006 and December 2012 were extracted by chart review, and the overall and recurrence-free survivals of the patients operated by wedge resection, by segmentectomy and by lobectomy were compared using the univariate and multivariate Cox proportional hazard model. A stepwise backward elimination method with a probability level of 0.15 was used to select the most powerful sets of outcome predictors. For all analyses, a p-value<0.05 was considered statistically significant.

Results:Limited lung resection (wedge resection and segmentectomy) were selected for higher age patients, for lower respiratory function patients and for smaller size tumor than lobectomy group. By univariate and multivariate analysis, surgical procedure was not identified as independent risk factor for overall and recurrence-free survival.

Conclusion:In this study cohort, mode of surgical procedure did not affect the relapse risk and prognosis. The choice of procedures at our institute in this study period seemed to be appropriate.


© Nankodo Co., Ltd., 2019

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電子版ISSN 2432-9436 印刷版ISSN 0021-5252 南江堂

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