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薬物療法抵抗性の心原性ショックに対しては,大動脈内バルーンパンピング(IABP)や経皮的心肺補助(PCPS)などの経皮補助循環装置が用いられてきたが,過去20年間で経皮補助循環装置における新しいテクノロジーは出現しておらず,治療の選択肢は限られていた.既存の補助循環装置では血行動態の改善と心筋の負荷軽減を同時に,かつ低侵襲に行うことはむずかしく,それらを実現できるデバイスとして左心室から大動脈へ直接血液を送り出す経皮的補助人工心臓Impella(日本アビオメッド社,東京)が開発された.
Intraaortic balloon pumping(IABP)has been used in more than 20,000 cases annually in Japan and this old device may be used differently by less invasive approach via axillar artery, which enabled the patients to ambulate for rehabilitation. Impella, a newly developed microaxial blood pump, has been used as a less invasive left ventricular assist device in more than 50 case in the last 6 months since its approval in Japan. Our experiences in 11 patients indicated that it improved not only cardiac output, but also cardiac function, which resulted in cardiac recovery in 5 patients. Technical advances in less invasive mechanical circulatory support may play an important role in thoracic surgery as well as cardiology.
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