小脳性認知情動症候群に対する認知機能検査の臨床的有用性の研究

The clinical usefulness of the Mini-Mental State Examination for cerebellar cognitive affective syndrome

要旨：Cerebellar cognitive affective syndrome（CCAS）は小脳障害によって引き起こされる神経心理学的な症候群であり，症状として遂行機能障害，視空間認知障害，言語障害，感情障害の4徴候が特徴である．小脳障害において運動症状を中心に呈し認知機能障害が一見目立たない症例では，高次脳機能に問題がないと判断されることが多い．本研究ではCCASの高次脳機能障害を，小脳損傷のみを呈した12名の患者を対象としMini-Mental State Examination（MMSE）にて測定した結果，全症例でCCASを認めた．本研究にて小脳損傷のリハビリテーションでは運動機能だけでなく神経心理学的評価を行うことが重要であり，その際にMMSEを用いることの有用性が示された．

　Cerebellar cognitive affective syndrome (CCAS) is a neuropsychological syndrome caused by a cerebellar disorder and is characterized by four symptoms: Executive function disorder, impaired visuospatial ability, speech disturbance, and affective disorder. A patient exhibiting predominantly motor symptoms after cerebellar injury, in whom cognitive impairment is not significantly apparent, is judged to have no problem in higher brain function in many cases. This study assessed higher brain function of 12 patients with CCAS showing only cerebellar injury using the Mini-Mental State Examination (MMSE). Consequently, CCAS was found in all patients. This study demonstrated the importance of performing not only motor function assessment but also neuropsychological assessment for rehabilitation from a cerebellar injury and the usefulness of MMSE in the assessment.