運動失調を伴う神経変性疾患の円模写軌跡測定値とBarthel indexの関連

Association between measurements of circle copying and the Barthel index in patients with neurodegenerative disease accompanied by ataxia

要旨：上肢に失調症状を認めた神経変性疾患患者39名に，円模写軌跡測定値分析をおこなった．円模写軌跡測定値とバーセルインデックス（以下，BI）値の相関を調べて模写因子を確認し，重回帰分析によってBI値に関連する模写測定値を特定した．BI値への関連は，「ずれ標準偏差」が特異的であり，因子分析で得られたずれ標準偏差，描画速度平均値，プラス偏角標準偏差の要因を用いた重回帰式が得られ，適合度の良好な予測式が特定された．したがって，失調症状患者のBI値は模写円とのずれのばらつきに最も関連があり減少，模写速度が速いほど増加，外側にはみ出す角度のばらつきが大きいほど減少する関係が示唆された．

　Analysis of circle copying was performed on 39 patients with neurodegenerative diseases displaying ataxia of the upper limbs. The correlation between the measured value of the copied circle and BI value was analyzed, factors involved with copying were investigated by factor analysis, and the measured copy value influencing the BI value was identified through multiple regression analysis. Regarding the influence on the BI value, the standard deviation of divergence from the circle was specific, and the following multiple regression equation was obtained adopting one element from each of the factors identified by factor analysis: BI value=105.42－299.37 X₁＋4.99 X₂－0.69X₃ (X₁=“standard deviation of divergence”, X₂=“mean speed of drawing”, X₃=“standard deviation of plus declination”). The equation was established as a prediction formula with a favorable fit. The results suggest that, in ataxic patients, the BI value is most markedly influenced and reduced by the variation of divergence from the circle, increases as the copying speed rises, and decreases as the angle variation increases.