CONFERENCE ON THE CHEMISTRY OF MUSCULAR CONTRACTION 1957
A Tropomyosin-like Fragment of Denatured Myosin
K. LAKI
1
1Nationl Institute of Arthritis and Metabolic Diseases, National Institutes of Health, Public Health Service, U. S. Department of Health, Education, and Welfare
pp.129-132
発行日 1958年4月15日
Published Date 1958/4/15
DOI https://doi.org/10.11477/mf.2425906002
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When trypsin or chymotrypsin acts on myosin, two kinds of fragments(3 pieces/ mole),the so-called meromyosins are produced(1〜5). It was found by A. G. Szent-Györgyi that when alcohol denaturation is applied to L-meromyosin about 60% of it remained undenatured and crystallized in needles(6).
In the experiment reported here a reverse approach was tried. The myosin was first denatured by a procedure similar to that used by Szent-Györgyi to denature L-meromyosin(7).
Copyright © 1958, THE ICHIRO KANEHARA FOUNDATION. All rights reserved.