ガンマナイフ治療が奏効した側頭骨軟骨芽細胞腫の1例

Gamma Knife Radiosurgery for Temporal Bone Chondroblastoma：Case Report

Ⅰ．はじめに

　頭蓋骨原発軟骨芽細胞腫は稀な疾患であり，全摘出できれば予後は良好であるが，残存腫瘍に対する治療については意見が分かれている．放射線感受性は良好との記載が多いが，具体的な報告例は必ずしも多くない．今回われわれは側頭骨原発軟骨芽細胞腫の残存腫瘍増大例に対してガンマナイフ治療を行い，良好な結果が得られた1例を経験したので報告する．

　A case with chondroblastoma arising from the right temporal bone was reported.

　A 52-year-old woman demonstrated residual tumor growth after surgical excision. The patient presented continuous right temporalgia and right facial twitch while opening her mouth. The tumor was an expansile mass (tumor volume: 12.8cm³) and showed homogeneous hypo-intensity on T1 and T2-weighted images, but little contrast enhancement. The patient underwent gamma knife radiosurgery (GKR: marginal dose: 12Gy, maximum dose: 24Gy). One month later, her symptoms improved completely. The size of the tumor was reduced to 6.4cm³ twenty months after GKR. The patient has been free of recurrence and side effects for four years since GKR.

　GKR may be useful to control residual chondroblastoma of the skull after surgery.