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I.まえがき
小児の四肢伸側にみられる毛嚢性丘疹で,比較的急速な経過をしめし,かなりの比率に感冒などの前駆症状を認める例は往々にして経験される。古くは急性紅色苔癬の一亜型とされていたようであるが,近時ヨーロッパ諸国で注目をひき,その臨床像,病因等につき検討されると共に独立疾患となす観方がつよくなつてきた。
即ち1953〜1955年,Gitanotti1)はミラノで従来報告をみない独自の病像を呈した3例の小児例を報告し,1956〜1957年にGianotti及びCrosti2)は"Akrodermatitis papulosa eruptiva infa—ntilis"として文献上初めて記載した。1960年にはGianotti及びCrosti3)により同様症状を呈する症例約60例が集められ,"Gianotti-Crosti Syndrom"と命名され,その外貌が愈やく明らかとなつてきた。
Six cases of Gianotti-Crosti's syndrome and suspected of this condition were reported. Case 1 and case 2 were one-year-old boys with typical manifestations on the extremities and face.
Although the other 4 cases had some questionable points about age and localization of the eruption, the skin manifestations which followed upper respiratory inflammation and the morpho-logic characteristics of the eruption were compatible with those of Gianotti-Crosti's syndrome. Histopathologic specimen of the eruption of case 2 revealed an inclusion body which supports the virus origin of this disease.
Review of reported cases in Europe and America was performed, and differential diagnosis was discussed.
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