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A case of episcleritis diagnosed with SAPHO syndrome 16 years after the onset Hideaki Kawakami 1 , Masayuki Inuzuka 1 , Kiyofumi Mochizuki 2 1Department of Ophthalmology, Gifu Municipal Hospital 2Department of Ophthalmology, JA Gifu, Gihoku Kousei Hospital pp.292-297
Published Date 2024/3/15
DOI https://doi.org/10.11477/mf.1410215114
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Abstract Purpose:To report a case of SAPHO syndrome diagnosed 16 years after the initial onset of episcleritis.

Case:A 51-year-old female presented with ocular pain and redness in the right eye. Her medical history included chronic tonsillitis, erythema nodosum, and palmoplantar pustulosis. There was no abnormality in the intraocular region of the right or left eye. After being diagnosed with episcleritis in the right eye, her right eye was cured with steroid eye drops and oral medication. Ten years later, she came to our hospital again with episcleritis in the right eye, and since then, episcleritis has been seen 7 times in the right eye and 7 times in the left eye. With steroid eye drops, oral medication, and occasional ocular injections, the condition of her eyes always resolved within a few weeks. During a physical examination 16 years after the initial onset of episcleritis, computed tomography(CT)revealed bone sclerosis, thickening, and polyarthritis in the sternum and spine, and a diagnosis of SAPHO syndrome was made based on chronic tonsillitis, palmoplantar pustulosis, anterior thoracic lesions, and spondylitis.

Conclusion:SAPHO syndrome should be considered as a differential diagnosis in patients with episcleritis of unknown cause and recurrent flare-ups.


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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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