Japanese

Intravitreal injection of tissue plasminogen activator for central retinal vein occlusion with cystoid macular edema Hirokazu Ohashi 1 , Hirokazu Nishiwaki 1 , Kazuaki Miyamoto 1 , Hideyasu Oh 1 , Noriko Miyamoto 1 , Tomoaki Murakami 1 , Hideo Nakanishi 1 , Hitoshi Takagi 1 1Dept of Ophthalmol and Visu Sci,Grad Sch of Med,Kyoto Univ pp.289-294
Published Date 2004/3/15
DOI https://doi.org/10.11477/mf.1410100527
  • Abstract
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 We treated 13 eyes of central retinal vein occlusion(CRVO)by intravitreal injection of tissue plasminogen activator. All the eyes had clinically significant cystoid macular edema. The interval between onset of CRVO and treatment averaged 1.3month. The logMAR visual acuity averaged 1.19 before start of treatment,0.84 after 1month,0.80 after 3months,and 0.72 after 6months. The differences were significant(p<0.01). The macular thickness,when expressed asμm,averaged 928 before treatment,288 after 1month,293 after 3months,and 213 after 6months. The differences were significant(p<0.01). Complications,including retinal detachment or vitreous hemorrhage,were consistently absent. The findings show that intravitreal injection of tissue plasminogen activator is easy and safe and that it promises to be effective to improve visual acuity and cystoid macular edema in CRVO.


Copyright © 2004, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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