下肢に発生した顆粒細胞腫の1例

Granular Cell Tumor Arising in a Lower Extremity. Case Report

　顆粒細胞腫は軟部腫瘍の0.5％を占める非常に稀な軟部腫瘍であり，特に頭部，頚部，舌を主体としたあらゆる部位の皮内，皮下，粘膜下に主に発生するとされている．この腫瘍は免疫組織学的手法により神経原性であることが報告されている．今回われわれは54歳の女性の右大腿近位に発生した稀な良性顆粒細胞腫についてFDG-PET（陽電子断層撮影）を含めた単純X線像，CT，MRI，ガリウムシンチグラフィなどの画像所見と，手術後の切除標本についての検討を行ったので報告する．

　Granular cell tumor is a rare soft tissue tumor, and it is estimated to account for 0.5％ of all soft tissue tumors. This tumor usually occurs in the dermis, subcutaneous tissue, and submucosa anywhere in the body, but especially around the head, neck, and tongue. Immunohistochemical analysis has indicated that granular cell tumors arise from Schwann cells. We report a case of granular cell tumor of the lower extremity in a 54-year-old female, and also present the radiological information for the preoperative diagnosis, including FDG-PET evaluation, in addition to the radiological modality of plain film, CT, MRI, and gallium scintigraphy, and the pathological findings in the resected specimen.