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Deep Peroneal Nerve Palsy Associated with Hypothyroidism Toshikazu Yasuoka 1 , Takanori Yokota 1 , Hiroshi Tsukagoshi 1,2 1Department of Neurology, Tokyo Medical and Dental University Keyword: deep peroneal nerve palsy , hypothyroidism , pretibial edema pp.563-566
Published Date 1993/6/1
DOI https://doi.org/10.11477/mf.1406900498
  • Abstract
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Carpal tunnel syndrome is well known to be associated with hypothyroidism, but other mononeuropathies have been rarely reported. We report a 65-year-old male who showed right deep peroneal nerve palsy caused by hypothyroidism.

The patient was admitted to our hospital because of general fatigue and right drop foot. On admis-sion, bilateral pretibial pitting edema was observed, predominant on the right side. There was no muscle contraction in the right anterior tibial muscle and extensor hallucis longus in addition to slight weak-ness of the proximal muscles ; whereas, muscle atrophy of the anterior tibial muscle was not noted. There was no sensory disturbance. On an electro-physiological examination, there was no muscle action potentials by the stimulation of the right deep peroneal nerve. Other nerves showed normal results both in the conduction velocity and in the compound action potential. Two months after the administra-tion of levothyroxine sodium (0.025 mg/day) , the right deep peroneal nerve palsy was completely recovered, associated with disappearance of pretibial edema.

It is not yet determined which of axonopathy or demyelination is dominantly responsible for neu-ropathy associated with hypothyroidism. These results suggested a conduction block in deep pero-neal nerve associated with focal edema. It is nece-ssary to consider hypothyroidism as well as tra-uma, diabetes mellitus, and vasculitis when inves-tigating mononeuropathy of deep peroneal nerve.


Copyright © 1993, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 2185-405X 印刷版ISSN 0006-8969 医学書院

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