Two Case Reports of Schizophrenia with Polydipsia Successfully Treated with Quetiapine Keiko NAGATOMO 1 , Ryuichiro TAKEDA 1 , Syohei MAKITA 1,2 , Kayo KIMURA 1,2 , Hiroyuki YUJI 2 , Seigo MERA 2 , Shigeki KURAYAMA 2 , Yasushi ISHIDA 1 1Department of Psychiatry, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan 2Miyazaki Wakahisa Hospital Keyword: Schizophrenia , Polydipsia , Antipsychotics , Quetiapine pp.483-489
Published Date 2012/5/15
DOI https://doi.org/10.11477/mf.1405102174
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 Polydipsia is a potentially fatal condition observed in patients with chronic psychiatric illness, especially schizophrenia. In general, management of this condition is difficult, as patients are uncooperative and secretive about their water intake, but important in terms of the associated complications. Several strategies, including involuntary fluid restriction and isolation or restriction have been used for the treatment of this condition with inconsistent results. Antipsychotics have also been used in the treatment of polydipsia. However, their role remains to be delineated. Herein we present two schizophrenia cases with polydipsia that were successfully treated with quetiapine. This report suggests the possible effectiveness of quetiapine for polydipsia in schizophrenics.

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