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症例は18歳,女性.13歳より僧帽弁逸脱症を指摘され,1991年6月発熱・咽頭痛が出現し抗生剤で消長を繰り返していた.12月当院受診時より胸部X線写真での心拡大の進行(心胸郭比52%より70%),心エコー図での心嚢液の増大を認め,直視下ドレナージを施行した.性状は血性(Hb 2.3g/dl)で非膿性(WBC 1,500/mm3),総蛋白5.7g/dl,LDH 719IU/l,糖107mg/dlで,一般細菌,真菌,結核菌,悪性細胞は検出されなかった.胸水は非血性浸出性で無菌性であった.血液培養にてグラム陽性球菌が検出され,感染性心内膜炎と診断し抗生剤の投与を開始した.心エコー図では僧帽弁前尖は逸脱しvegetationの付着を認め,左室壁運動は正常,弁輪,心筋膿瘍は認めなかった.血液培養は陰性化し,心嚢液は再貯留しなかった.慢性に経過した感染性心内膜炎に無菌性心外膜炎を合併した.予後良好に経過し,ウイルス感染や免疫学的な機序による無菌性心外膜炎が疑われた.
A case of infectious endocarditis with aseptic pericar-ditis was reported. The patient was an 18-year-old female who had had mitral prolapse. She was referred to our hospital because of progressive cardiomegaly in chest X ray. Echocardiography showed a large amount of pericardial effusion and mitral vegetation without abscess both in the mitral valvular ring and the myocar-dium. Drainage for the pericardial and pleural effusion was carried out. There were no septic findings in eitter effusion. After the prescription of antibiotics for the causal streptococcus, blood culture became negative and pericardial effusion did not recur. The pericarditis was suspected to be caused by either immune mechanism or viral infection.
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