Risk Factor for Lymph Node Metastasis of Submucosal Invasive Carcinoma Naoko Tsuji 1,2 , Shingo Ishiguro 1 , Tsutomu Kasugai 1 1Department of Pathology, Osaka Medical Center for Cancer and Cardiovascular Diseases 2Department of Gastroenterology, Midorigaoka Hospital Keyword: 胃sm癌 , リンパ節転移 pp.41-47
Published Date 1997/1/25
DOI https://doi.org/10.11477/mf.1403104949
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 To investigate the risk factor for lymph node metastasis of submucosal invasive gastric carcinoma, we examined 679 cases of surgically resected submucosal invasive gastric carcinomas. Macroscopically, 28% of elevated with Ⅰ type cases were node positive, while in cases of depressed without ulcer, 12% were positive. Histologically, the rate of lymph node metastasis was high in papillary adenocarcinoma (26%) and mucinous adenocarcinoma (30%), while it was low in well differentiated tubular adenocarcinoma (tub 1) (16%). Histologic type of mucosal and submucosal components were separately. described in 296 cases smaller than 4 cm. When mucosal histologic type was tub 1 and macroscopic type was depressed without ulcer, no cases were node positive even if the tumor had deeply invaded the submucosa. Cases included in this category were thought to be an indication for conservative therapy such as endoscopic mucosal resection or laparoscopic gastrotomy.

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